The plant Osbeckia octandra (L.)DC. (family Melastomataceae), which is locally known as ‘Heen bowitiya’ is one of the endemic plant species in Sri Lanka renowned for its medicinal importance. Also it had been referred to as ‘Kuruvina’ in the past. This plant has been extensively used in traditional medicinal system in Sri Lanka for treating several liver disorders such as cirrhosis, hepatitis, hyperlipidemia and diabetes mellitus, jaundice, hemorrhoids and ascites. Most importantly, chronic liver injury has become a major health concern world-wide and at severe condition, only remedy remains the organ transplantation which again is hampered by many factors. Complementary and alternative medicines included with herbal therapies are drawing more attention recently in decelerating progressive liver damage.
Words - Dr. D. M. R. G. Mayakaduwa, Department of Plant Sciences, Faculty of Science, University of Colombo
Prof. S. K. M. K. Herapathdeniya, Department of Ayurveda Pharmacology,Pharmaceutics and Community Medicine, Faculty of Indigenous Medicine, University of Colombo
Medicinal properties associated with Osbeckia Octandra have also been investigated at a depth in a more scientific context. Several biochemical and histopathological studies have been able to prove the potential of Osbeckia Octandra for treating liver cirrhosis induced by different factors as the plant extract in different forms exhibited strong hepatic anti-fibrotic effects.
Moreover, Osbeckia Octandra has demonstrated anti-cancer potential during cell culture investigations with oral carcinoma cells. Anti-angiogenic properties associated with above plant material were also proven in recent experiments which could be useful in developing integrated cancer therapies.
Osbeckia Octandra has demonstrated its potential in oral hypoglycemic activity as well. Ethnomedicinal knowledge coupled with evidence-based medicine could pave way to deliver more effective hepato-protective, anti-diabetic and anti-cancer drugs and therapies in future harnessing this invaluable medicinal plant.
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